Study: e cigarette users with substances linked to bladder cancer in urine Although research on cancer risks associated with vaping is still limited, a 2025 systematic review found substantial evidence that e cigarette exposure is associated with biomarkers reflective of cancer disease risk. This includes Vaping releases toxic chemicals, including heavy metals, as well as ultrafine particles that go deep into the lungs. These increase the risk of heart and lung disorders. vape juice without propylene glycol Vaping and smoking together increases lung cancer risk fourfold Oviedo couple works to make e cigs safer West Orange Times & Observer