The Binding of Isaac Four Souls Requiem Expansion And here's the other original drawing I said good bye to"Delirium" created for the Binding of Isaac: Four Souls card game. #bindingofisaac #foursouls UPDATED Every card we got to see in 4 Souls : r bindingofisaac The Binding of Isaac: Four Souls and its Requiem expansion will take you to dark places! Big Boss Battle (B3) If anyone plays the binding of isaac the video game, there's also Binding of Isaac four souls card game, just got the new booster pack. I've spent about $1000 dollars on this ISAAC TREASURE CUSTOM DECK